Saturday, August 31, 2019

Jymique Easter

Easter is celebrated the world over to mark the resurrection of Jesus Christ†. Also Easter is observed any. Veer between March 22 and April 25 of every year. Also a good question is what does the word Easter even mean, Who started this tradition, and where did it come from, and why was it made Foster 2 Television Networks tells all about Easter and why we celebrate it. It tells that celebrate Easter because of Jesus Christ resurrection. In this website it tells about how Easter is called a movable feast because it does not fall on a set date every year.I can SE this source very effectively in my paper because it tells about the origins of Easter. â€Å"Easter. † History. Com. Television Networks, n. D 28 Septet. 2014. In History. Com. A&E In this website it tells about the dates of Easter, and this is helpful information considering that Easter does not fall on the same date every year. In fact this source does not just help me, and it helps all the people out there who want to know what day Easter falls on. In this source it also talks about how Easter is a â€Å"blessed time for the faithful to celebrate life, death and resurrection for the savior. † â€Å"Easter 2014 Dates.Easter Dates for 2014 and Information. N. P. , n. D. Web 28 Septet. 2014. An this website it talks about the origins, the meanings, and practices of Easter, and it says that â€Å"Both Christian and Pagans have celebrated death and resurrection themes Foster 3 following the Spring Equinox for millennia. † can use this source as a very powerful tool in my research paper since it goes deep down into the practices of Easter. â€Å"Origins, Meaning and practices of Easter. â€Å"Easter. N. P. , n. D. Web 28 septet. 2014. While researching the holiday Easter, I have found some very helpful information for me and everybody else to understand Easter a little bit more.I have learned a lot of interesting things about Easter such as when it started, why it started, and why it is so important. â€Å"Easter is a day that is honored by nearly all contemporary Christianity and is used to celebrate the resurrection of Jesus Christ†. Easter usually involves a family gathering followed by a big feast with a Easter ham for everybody to enjoy. Also some family go to church for early service to start off their Easter Sunday. Last but not least, just about every family has a Easter Egg hunt to finish off there Easter Sunday.A Easter egg hunt is when the a family boils eggs, then decorates the eggs with fancy designs. After that they hide the eggs around their neighborhoods, yards, parks, or where ever the family thinks is a good place to hide the Easter Eggs. That is Foster 4 when all the children go scavenging for the decorative Easter Eggs. Most people do not know why they color or hide Easter eggs. The egg was a sacred symbol among the Babylonians. The Babylonians believed that a large egg fell from the Euphrates River, an that the Goddess Stare wa s hatched. So the after that the egg came to be symbolized as the Goddess â€Å"Easter'.The name Easter has its roots in polytheistic religions, most people prefer to say Resurrection Day rather than Easter. As you know Easter falls on different dates every year in the months of March or April. The chosen date comes from a formula established by the Roman Emperor Sophistication The Great an the Council of Niece in A. D. 325. You can use this formula to find Out the date that Easter fall on every year. â€Å"According to this rule the latest possible date for Resurrection Sunday is April 25, next occurring in 2038. The earliest is March 22, in 2285. So you see there is a lot of history to Easter.

Friday, August 30, 2019

Rear Window Essay

In the 1950’s film Rear Window, director Alfred Hitchcock sets his entire work looking through a man, L. B. Jeffries’ rear window. Because of his broken leg, Jeffries is confined to his apartment, and even to his wheelchair. It is here, in his apartment, that the protagonist watches, or even spies on his neighbors. He draws conclusions on these people, but from a distance: across the apartment-building courtyard. In addition to this physical distance separating Jeffries from his neighbors, his perspective, too, distances him from his conclusions. Only seen through the glass of a window and the lens of a camera, Jeffries’ point of view is confined to only a single vision. We see that this single vision, however, provides Jeffries with an ample amount of information. The avant-garde cinematography combined with the original plot creates a new mean to film. Alfred Hitchcock’s innovative Rear Window allows the audience to bring their own experiences to the film: just as Jeffries draws conclusions on his neighbors from a distance, man too establishes his own perspective in the real world, and brings this experience to the film to understand its meaning. In Rear Window’s opening scene, the camera slowly scans the setting that will surround L. B. Jeffries for the rest of the film. It pans over many apartments, all full of people doing different activities, going on his or her daily routine. This seemingly normal day in the New York City apartment complex gives the audience a sense of familiarity with the setting, and the people that live there. As seen through Jeffries’ rear window, this scene foreshadows the rest of the film; little does the audience know that what seems ordinary, a simple window, actually reveals more: crime. Because the film’s title is Rear Window, this specific window indeed holds some significance. One could say the window hides Jeffries from the real world, as he is confined to his own apartment. While on the other hand, it could be said that the window submerges the protagonist into this world. I believe that the window serves as both tools: as the film’s antagonist, Thorwald sees Jeffries spying on him, Jeffries closes his window and retreats into his apartment- escaping the real world. On the contrary, however, the audience sees Jeffries constantly peering through the window, using the pane of glass to almost enhance his vision, and draw his conclusions. Just as the window both hides and reveals L. B. Jeffries, so does his camera lens. Throughout the movie, Jeffries uses his lens to get a better vision of his neighbors and their activity. Yet the protagonist uses his camera in an unconventional way- rather than using it to take a snapshot of a certain instance, Jeffries uses the camera lens simply to magnify his vision, and gain a deeper understanding of his neighbors, especially Thorwald. Just as L. B. Jeffries, I too have drawn conclusions on others from a distance. Attending a small high school comprised of only one thousand students, I have a superficial understanding of most of my peers. What seems to be a small distance separating my peers and I, actually acts as a barrier, just as Jeffries’ window and camera do. Recently, I was formally introduced to a peer of mine, who I simply knew by association. I had heard people give their own opinions about her, critique her, or speak highly of her- I had yet to draw my own conclusion of her. It was only until I spent a few days with her, and had conversation with her that I could finally create my own opinion. For years I had an imprinted opinion of her in my head, but as I finally broke through the barrier, my rear window, I could either support or refute my assumption. Right on some accounts and wrong on others, I, like L. B. Jeffries, drew conclusions with a barrier; we both had been living behind our rear window.

Modern family values

Family dynamics have rapidly been changing and evolving over the last two hundred years, with far-reaching consequences on individuals and societies as a whole. Whereas before the industrial revolution, children used to live and work with their parents within the home to learn the family trade that would support them and future offspring, now parents spend a good majority of their days at work and children at school. Additionally, there is no longer a â€Å"normal† family model of two heterosexual spouses and their children to comprise the average home. As noted by economist Nancy Barret inDecline of the Family: Conservative, Liberal and Feminist Views, there is no longer one family model that is more dominant than another. (Giezle, Janet D. , 88) The opinions regarding the reasons for such familial shifts are as diverse as the many family models now present. While the opinions of the reasons for such changes in the family may differ, there is a consensus that such changes cor relate with the general upward trend of violence, anti-social behavior, divorce rates, teen pregnancies and addiction habits among parents and especially children.Conservatives argue that such negative behavior epresents a moral decline perpetuated by broken homes and poverty caused by young, unwed parents. They offer a return to traditional family standards and values as a solution to such problems. to such problems, a reversion to a traditional family model is not a viable solution for every family and, therefore, the solution lies in building up communal support for all family types by stressing the importance of families and deemphasizing the individual.Using these two perspectives put forth in Giezle's Decline of the Family, this paper will analyze a true narrative of my younger sister who, after failed marriage, attempted to raise a son, attend university and procure a Job after graduation. I have four siblings, and my sister, Beth, is the youngest. Our mother was a single mot her who supported her five children by, first, relying on government support through welfare and charities, until she was able to gain a Job working night shift for the post office. The Job offered long, exhausting hours but Just enough money that we no longer required government assistance.Though my mother was able to support us materially, she was still often stressed over money matters, running a household nd trying to meet the needs of her children. Our home environment was very stressful. Our mother needed to sleep during the day, so household responsibilities were left to us children. Though we were children, it was expected of us to grow up rather quickly, as we had to rely on and look after each other. Emotions were put aside in favor of getting by, paycheck to paycheck. By the time each of us became a teenager, it was expected that we would find a part-time Job to help cover some of our own expenses. lerical position, my brothers and I into the military, and Beth, surprisin gly, decided to elope with her oyfriend, who had also Joined the military. It was, as she has reflected on it, an act of desperation to escape a stressful home and the fear of no Job prospects and absolutely no way to fund a college education. Her husband was trained by the military in basic mechanical duties on military planes and they lived in Texas for a year before they expected their child. With his military contract up, they returned to the Pacific Northwest with the idea of him finding steady work to support their family.The work was hard to find. The mechanical skills her husband had acquired in the military did ot transfer to the civilian world. Temporary, part-time Jobs were not a reliable source of income to prepare for their child. My sister took up work in a restaurant right up until she gave birth in order to help with the finances. After she gave birth, the question of whether to return to work raised several issues. His income alone was not enough on which to live. T herefore, they needed a second income. However, they could not afford to hire a sitter to cover those work hours.Further, they were informed by the state that the additional income would raise them above assistance level for food and edical benefits. They were in a catch-22, so to speak. They needed to earn more money, but if they did, they would second income. The strain of money issues, raising a newborn, and the typical relationship problems that accompany young people and rash decisions, brought their marriage to an end when their son was Just one. My sister was in a very difficult position. She had a son to raise, but on no place to live, no college education, and very little work experience. She lived with me while she filed for state benefits.Over the course of eight months, she secured an apartment, enrolled in chool and began the work-study program there to earn a bit of money. However, the state assistance would only continue if she were in a vocational program at the comm unity college. The incomes of such vocations threatened to put her back in the same predicament she and her husband had been in†not enough to get by, but Just enough that the state could offer no assistance. She gave up the state assistance and her apartment to move back home with our mother, who agreed to baby-sit while my sister attended the University of Portland and worked on campus there.She still eceived medical insurance for her son, and a small stipend for food. After four years, she graduated and landed a Job that now supports her and her son. It would not have been remotely possible without the support of state programs, generous student grants and constant support from her family members. From a conservative's perspective, issues such as teen pregnancy, divorce and couples having children while being unable to support them are all marked signs that society has shifted from traditional family values.A conservative would argue that the moral declination of society is exemplified in the selfishness of individuals ho place little to no value on the family unity. Further, they argue that the cultural attitudes toward unwed parents and those on state assistance have become too tolerant, rewarding them with welfare assistance programs that do nothing but lower community standards and teach dependence instead of self-reliance. (Giezle, 77) Cons

Thursday, August 29, 2019

Database in an Organisation Essay Example | Topics and Well Written Essays - 1500 words

Database in an Organisation - Essay Example This study covers various aspects related to database systems in the BMI healthcare hospital located in the United Kingdom. An analysis of database applications shows that a database system is an integral part of any health care organization. The key functions of a database system are also determined which include recording the relevant data, processing of data, organizing the collected data, and assisting departments of an organization in the different business processes. The result of the study shows that an efficient database system plays a key role in the progress and development of BMI healthcare hospital. 1. Introduction Data or up to date information is of critical importance for any company or organization. It not only plays a key role in the success of an organization but also makes the organizations compete with other firms in a competitive environment. However, companies need to manage the data in an appropriate way in order to make a good use of it. Therefore, information technology professionals have developed database systems, which not only help the organizations manage the data properly but also make the organizational activities efficient and well organized. It is due to the utmost importance of database systems that almost every company or organization of the current business environment has implemented efficient database systems in order to manage data in an organized way. In this paper, we will discuss what database systems are and what role do they play in the success of an organization. 2. What is Database? Before going into the discussion related to databases and their uses in organizations, let us get a better understanding of what database actually is. Date, Kannan, and Swamynathan (2006, p. 6) state, â€Å"A database is basically a computerized record-keeping system†. Database is a record of important data or information, which an organization requires to run different business processes and activities. â€Å"A database can be limited to a single desktop computer or can be stored in large server machines, like the IBM Mainframe† (Satalkar, 2009). Database systems are not like spreadsheets. Some of the functions, which make database systems different from spreadsheets, include retrieval of records that match certain criteria, updating of records in bulk, cross-referencing records in different tables, and performing complex aggregate calculations (Chapple). Database systems help the employees retrieve some specific data from the records. Database systems also help the doctors prepare reports based on recorded data and assist them in performing complex calculations needed to analyze different case histories. 2.1 Types of Databases â€Å"Two of the most popular database systems used by web developers today are MySQL and Microsoft's MS SQL server† (Hobach, 2008). There are various types of databases depending on the structure of data. Some most common types of databases include flat model database , network model database, hierarchical model database, and relational model database. The most commonly used type of database is relational model database. â€Å"In a relational database, information is stored in tables (often called relations) which help organize and structure data† (Martin, 2010). Companies use relational model database not only to store data but also to retrieve it when needed. Data is stored in the form of tables and each record stored in the table can have many fields. Using relational model

Wednesday, August 28, 2019

See the dise Essay Example | Topics and Well Written Essays - 500 words

See the dise - Essay Example Its economy is strong and prosperous. This country is regarded as one of the finest place for the tourism. It holds almost 80% non- nationals as stated by Boleat (2012). One of the cities of U.A.E, Dubai is known as ‘city of Gold’. Boleat(2012) also reports about the economy of this country by saying â€Å"Dubai has a highly developed economy†. With increasing living standards and lifestyle people have become conscious about their lifestyles and looks. The rapid economic growth of the country has also contributed to improved diets and thereby obesity (Faust, 2012). This information from different resources suggest that population of U.A.E due to the availability of different fast foods and high scale income is directing themselves towards obesity. This fast growth in the obesity in U.A.E ‘s population has made them consious of their health. Different researches in this field have proved that people of U.A.E are becoming health – conscious and they are demanding for clothes that are specifically sports-outfits in which they can easily work out. This information about the need of opening sports clothing company in UAE is provided by Nasser who is form United Arab Emirates. He translated the local papers from there and provided the relevant information which was needed for the research. His information was a guide to study about the living standards, lifestyle, population, education, religion, language etc.Before analyzing the fitness adverstisements in the local megazines and the newspapers, the ethnographic research on the people of U.A.E was necessary. The conclusion drawn upon the information about the people was done with the help provided by Nasser. As U.A.E’s population consists of 80% of non – nationals; multi – cultured people live there. People are mostly Asians, mainly from Pakistan, India and Bangladesh. The languages spoken in this country are mixed Asian languages by the people. Apart from those languages English also

Tuesday, August 27, 2019

Travel the World - Letter to a Friend - Assignment

Travel the World - Letter to a Friend - - Assignment Example nding money and time traveling to the City was, therefore, to experience the culture and art of London, to learn the various kinds of art within the city that may have influenced Albert in his career. In his painting, Albert depicts ambient photographic-like scenery of a lake amidst rocky mountain cliffs with grazing deer on the shore in the foreground. The cheap means of travelling to London from Huston Texas was through the Turkish airlines that cost $610 to and fro. The great London atmosphere also extends its hotels with varying affordable rates. Within the city of London, I am staying at the Central Park Hotel, a three star hotel located at the heart of the city that costs  £43 per night (FareCompare.com). London is the capital city of the England in Europe popularly known for its monarchy system under the rule of a queen. There are nearly over 300 languages spoken in the city, however, its main culture mainly ties around the arts, museums and various festivals. In particular, as for architecture, London prides itself of a number of landmarks and cultural iconic objects that are globally associated with the city such as the Big Ben, as well as the Buckingham Palace. The city is also popular for the fast foods vendors that specialize in making the burgers, pies and pizza that forms one of the main popular foods among most city dwellers and workers. In terms of entertainment, the city is best recognized for its particular preference for rock music dating from the 1960s and is the home for various globally renowned rock bands and musicians. The city is also home for some of the globally recognized teams in the game of soccer. Like other major cities across Europe, London has an oceanic t emperate climate with the four climatic seasons like most of Europe (The Guardian). Albert made his iconic photograph-like painting using oil-based paints and soft brush to make the portrait on canvas measuring approximately six and ten feet in size. Albert gracefully employs

Monday, August 26, 2019

Conduct an external environment analysis for a company of your choice Essay

Conduct an external environment analysis for a company of your choice assessing the impact of the external environment on Human - Essay Example The main objective of external analysis is to identify the opportunities and threats in the environment. Identifying and exploiting the opportunities and minimizing the threats, which are hindering performance can help the organization achieve its strategic competitiveness (Hitt, et al, 2009). This external environment has its impact on business strategy and hence on the human resource strategy as well. This paper aims at conducting the external environment analysis of Toyota and studies its impact on the human resource policies and practices of the organization. This paper will make use of different matrices, methods and tools to conduct the industry analysis. Automobile manufacturing is a very significant industry which contributes to 10% of the world GDP. Globalization has resulted in increased pressure on the firms to achieve global competitive advantage. Automotive industry has recently witnessed large scale consolidation of organization resulting in mergers and acquisitions to capitalize the strengths of each market and organization. Most of the organizations in the automobile industry are doing business offshore. The automobile industry global competition is characterized by big three American and Japanese giants with the shift moving towards Japanese automakers which includes Toyota. Toyota is increasing its market share and becoming more dominant and less threatened by its competitors. An external audit of Toyota will reveal its opportunities and threats and its impact on the business and HR strategy. External Environment Analysis The external environment or the macro environment has a strong impact on the all activities and strategies of the organization. These factors include political, social, economic, legal, technological and eco-environmental factors. Two models are used to analyze the force and impact of these factors. These two models are called â€Å"PESTEL Analysis† and â€Å"Porters five forces†. An industry’s attractive ness is evaluated through Porter’s five forces model. According to the model the forces that affect an industry are the threat of entrants, threat of substitutes, bargaining power of buyers, bargaining power of suppliers and the level of rivalry among the existing competitors (Porter, 2008). The evaluation determines the attractiveness or unattractiveness of the industry and also helps in formulating strategies for obtaining competitive advantage. The attractiveness of an industry in turn determines the overall profitability of the industry measured through overall return on investment. It requires utilizing the existing industry environment to gain competitive advantage. Out of the five forces the strongest competitive force indicates the profitability of the industry and forms the most crucial part of strategy formulation. If the affect of forces is intense then the industry is said to be unattractive that is companies in the industry will not earn attractive return on thei r investments while if the forces are not intense then the industry is attractive and the companies in the

Sunday, August 25, 2019

Sanpshot for PR class Assignment Example | Topics and Well Written Essays - 500 words

Sanpshot for PR class - Assignment Example The campaign aims at encouraging them to seek appropriate support and care for psychological health concerns. Print materials including brochures and advertisement cards were used for informing veterans, service members and their families on the presence of help for psychological and other support measures (Ruolo, 2013). Real warriors collaborated with organizations and individuals to aid in spreading the resources and information on the help available to the affected as well as the avenues through which they can be able to access this treatment including Deployment Health Clinical Center, National Center for Telehealth and Technology, and Defense and Veterans Brain Injury Center. Mobile websites and an interactive website were the other strategies used to ensure access to campaign materials to the supporters of the campaign and ensuring the resources, videos, social media, live chat, and other outreach areas provided for the affected members of the community Social media were used in the Real warrior’s campaign through reaching out to military personnel and their families with information on psychological help and support as well as requesting other members to join the course The Real warrior’s campaign has been successful in meeting the needs of the audience to which the campaign was directed and has been able to achieve augmented numbers of veterans, family, and service men receiving treatment and rehabilitation. In my opinion, the campaign is well handled and received with an emphasis on the messages tailored for the veterans, service members, and their families. The messages of the campaign and objectives are well stated, and testimonial videos from military personnel and veterans suffering from mental illnesses are very compelling (Acosta et al., 2012). The campaign is creative and uses innovative measures coupled with technologically advanced

Saturday, August 24, 2019

Orozco's Short Story in the Classroom Essay Example | Topics and Well Written Essays - 1500 words

Orozco's Short Story in the Classroom - Essay Example Orozco's work is filled with material that is almost Kafka-esque in its absurdity. For example, People at this company must arbitrarily fill their day with what is in their inbox, no matter how long it would take, instead of simply changing their workflow. â€Å"You must pace your work. What do I mean? I’m glad you asked that. We pace our work according to the eight-hour workday. If you have twelve hours of work in your IN box, for example, you must compress that work into the eight-hour day. If you have one hour of work in your IN box, you must expand that work to ï ¬ ll the eight-hour day. That was a good question. Feel free to ask questions. Ask too many questions, however, and you may be let go†. This quote alone can be used to generate two exercises. First: Is Orozco's character an actual person, or intended to represent one? I think not. Orozco's introduction character is some dream figure, some devilish mockery, much like a character in a Dilbert strip. A Dilbe rt strip of the Pointy Haired Boss could be compared to Orozco's orientation with fruitful results. Second: Students could be asked to write a story that plays up the absurdity of everyday moments too. An exercise on Kafka, Dilbert and Orozco, creating a short story that uses magical realist elements to highlight absurdity in the real world, would be a fantastic exercise in composition. The orientation is being offered to the reader: It is second-person narration, and particularly skillful at that. Second-person narration is difficult for many reasons, not the least of which being the way that is constrains the likely description and characterization approaches. In a first-person narration, where the protagonist is the narrator, the reader is given easy insights into the narrator's mind. The narrator can tell what he thinks about people, what he sees, describe rooms and situations, and make clear his motivation. A third-person narration, either omniscient or not, can similarly descr ibe characters, environments, settings and motivations without seeming out of place or jarring. But a second-person narration will rarely have these elements, because most people do not say, â€Å"Do you see how that desk is brown and the chair is red? Enjoy the comfortable leather of the chair†. Making what the second-person storytelling says plausible is difficult, but Orozco accomplishes it beautifully. Orozco is able to describe a workplace without describing it specifically, both as emotional and physical setting. We learn about fire exits, the Mr. Coffee, and get a

Friday, August 23, 2019

Foreign Economics and National Economics Council Essay

Foreign Economics and National Economics Council - Essay Example If such legislation is passed, the manufacturing industry would be revived, unemployment would reduce, and the government would reduce expenditure on insurance for unemployment and social security. In case the bill is approved, the United States will not have contravened the provisions of the World Trade Organization (WTO) which provides that members can take any action that is intended to protect its security interests1. It is the department’s position that although these arguments hold considerable weight, the negative effects of such legislation will by far outweigh the positives. One of the anticipated negative effects is that these countries, mostly China will retaliate by imposing their own duties on the United States. For example, in 2009, the United States imposed a tire tariff on Chinese tires thus reducing the influx of these tires into the country and saving approximately 900,0002. The Chinese responded by exercising antidumping duties on American chicken parts. The antidumping duties cost the United States approximately 1 billion dollars3. Although more jobs will be created in the manufacturing industry, a same number of people, if not more, will lose their jobs in the retail industry. In addition, if the import tariff is imposed, the manufacturing industry will become crowded with everyone wanting to be a manufacturer, as a result, the quality of products will reduce and the cost of raw materials will go higher. As such, the protected products are bound to cost more if domestic production is inefficient or if the cost of buying raw materials is higher than before, meaning that the United States will not benefit from these tariffs. On a political front, the relationship between the United States and China will be strained thus derailing the effort by the former to get the latter to convince North Korea to do away with nuclear weapons. As Rosati & Scott write, since North Korea borders China, the support of

Thursday, August 22, 2019

Intellectual Property Right Essay Example | Topics and Well Written Essays - 8000 words

Intellectual Property Right - Essay Example Such protection has lead to the provision of additional funding for the research studies, enhances the efforts on the technological innovations and has also led to the creation of a number of new start ups. Generally the concept of IP covers the legal rights to any person or organization resulting from any intellectual property. The intellectual property deals with the intellectual activities in various fields including industrial, scientific, literary and artistic and the like. The countries across the world have developed legislations covering the protection of IP. These laws have been enacted at the national level for the following main reasons: The first objective is to give a statutory recognition to the creators of the moral and economic rights attached to their creations and also to specifically spell out the accessibility of the public to such rights. The second one is to discharge the responsibility of the government with respect to the promotion of creativity and the dissemination of the application of such creations. This way the government would be able to encourage a fair trading that may result in a balanced economic and social development of the country. In generic terms the IP law aims at protecting the creators and producers of intellectual goods their rights on such goods and services by granting rights to exercise control over the use of those creations for a defined period of time. However it is important to note that such IP rights do not apply to the physical object on which the IP rights may be applied but only on the intellectual creation as such. The IP protection normally extends to (i) Industrial Properties and (ii) Copyright on Intellectual Properties. 2.0 Fields of Intellectual Property Protection The above two areas of IP protection can be further classified into different fields. Inventions, trademarks, industrial designs and geographical indications are covered by Industrial Property. Copyright encompasses literary and artistic works including novels, Poems, films and musical creations. In this context it is important to understand different types of intellectual properties. 2.1 Different Types of Intellectual Properties The different types of industrial properties that need protection are: 1. Patents 2. Industrial Designs and integrated circuits 3. Utility models 4. Copyright and related rights 5. Trademarks 6. Trade secrets 7. Plant breeder's rights 2.1.1 Patents A patent is regarded as an exclusive right that is conferred on any person in respect of an innovation. The patent right has normally a duration of 20 years. A patent right is granted for a product or process which have the capacity of providing in general way of doing something or offering a new technical solution to a problem on hand. "An invention is considered "new" as long as it is not known to the public by any means (written or oral or in any other way), before its filing

The Humanistic and Cognitive Behavioral Applications of Psychology Essay Example for Free

The Humanistic and Cognitive Behavioral Applications of Psychology Essay Psychology as a scientific discipline can be divided into four major historical forces. The first historical force being psychoanalysis, the second force behaviorism, the third force humanistic, and the fourth force multicultural. Each historical force represents the zeitgeist or prevailing school of thought for its historical time, and each school of thought brought about the development of different theoretical applications and ideological approaches. This paper will focus on theorists and theoretical applications of the second and third historical forces. Behaviorism is the school of thought founded by John B. Watson and is the second historical force in psychology. The basis of behavioral psychology suggests that all behaviors are learned and therefore can be unlearned and changed. Watson, like most other behaviorists were of the mindset that only observable, or overt behaviors, should be studied because concepts such as emotion and cognition were too subjective (Cherry, K. 2011). Cognitive applications of behavioral psychology known as Cognitive Behavioral psychology or Cognitive Behavioral Therapy (CBT) differs from the orientation of Behaviorism in that it focuses on the mental processes, perceptions, and interpretations of the mind, as well as how information is retrieved. Cognitive Theorists believe emotions are triggered by thoughts and beliefs. It is in this mindset that Cognitive Behavioral psychotherapy was developed as a type of â€Å"talk therapy† which is clinically proven to be more effective than medication for treating insomnia, depression and several other psychological issues. One of the most notable Cognitive Behavioral theorists of modern day psychology is Dr, Albert Ellis. I focus on Albert Ellis and his theoretical applications because of their similarities to the foundations of Buddhist psychology. Albert Ellis founded Rational Emotive Behavior Therapy (REBT). Rational Emotive Behavior Therapy can be viewed as a philosophy of living, as well as a form of psychotherapy. Dr. Ellis also believed that unhappiness could be alleviated by learning to identify 4 types of irrational thinking and  cultivating â€Å"Universal Self-Acceptance† ( USA ) which overlaps Buddhisms â€Å"three marks of existence† ( annicca, anatta, dukha ) (Tsering, 2006). Dr. Ellis believed that â€Å"self-esteem† was an irrational and harmful concept for reasons similarly found in Buddhism. Many psychologists believe that self-esteem issues help or exacerbate most mental health issues. Dr. Ellis advocated replacing the concept of â€Å"self-esteem† with â€Å"Universal Self-Acceptance† (USA) (M.G.T. Kwee, 2006) Rational-emotive behavior therapy, or REBT, can perhaps be summarized by understanding the A-B-C model for psychotherapy. (Ellis, 1994) REBT says that the most commo n mistake people make is in assuming that adversity (A) is responsible, or causes, emotional consequences (C). For example, one might believe that doing poorly on a project at work (the adversity, or A) is what causes them severe anxiety and stress (the consequence, or C). The REBT therapist, however, argues that it is not the adversity (A) which causes the anxiety and stress (C), but rather it is the individuals perceptiontheir unrealistic and over generalized beliefs (B) about the adversity that causes the anxiety and stress. It was not that a person did poorly on the project, but rather her belief that she must do well on everything she does. This unrealistic belief that she must do well all the time led her to tell herself how awful it was that she did not do well. Thus, it was her perception that she did not do what must be done, and that it is awful that she did not do what must be done, that resulted in her feelings of stress and anxiety. While most people believe that A=C, the REBT therapist shows them that, in reality, A x B = C. If the therapist can adjust the clients thinking by ma king her realize that she doesnt always have to do well, or that its not really that awful that she didnt do as well as she would have liked, then her feelings of anxiety and stress may be lessened. (Ellis,1994) As a cognitive-behavioral mode of treatment REBT postulates that emotional and psychological disorders are largely the result of thinking irrationally, dysfunctionally, negatively, absolutely, or illogically. Furthermore, REBT theorizes that rational and irrational thoughts are incompatible. (Tsering, 2006) Humans are able to get rid of most of their emotional and mental unhappiness, inefficacy, or disturbance if they learn to maximize rational and minimize irrational ideation REBT holds that sustained negative feelings, such as intense depression, anxiety, anger, and guilt, are almost  always unnecessary to human living. (Ellis, 1994) After researching different aspects of Buddhist psychology it is my opinion that Dr. Ellis’ (REBT ) transcends multi-cultural borders and values. I find this approach to psychotherapy to be very beneficial and important in American psychology which historically has failed in many aspects to encompass other cultures and ideological approaches i n psychotherapies and treatments. Many similarities also exist between the ways that Taoism, Zen Buddhism, and the self-actualization theories of Rogers and Maslow. Both Maslow and Rogers described the self-actualizing person as one who has personal autonomy and who is free to make choices. The actions of the self-actualizing person are not determined solely by the physical and social environment, because a person has access to personal resources that are, in turn, growth promoting. According to Maslow (Maslow, 1968) ) the self-actualizing person does not avoid facing or acting on feelings or thoughts that are experienced. The self-actualized person of Maslow, Rogers, Zen Buddhism, and Lao Tzu feels a kinship with all human beings. These people care about others with a caring that is gentle and not moralistic. The humanistic approach of the third historical force in psychology reflects the self –actualization ideologies put forth in Buddhism and Taoism and suggested by Maslow and Rogers. Carl Rogers, created client-centered therapy, and designated unconditional positive regard (UPR) as one of the three conditions were necessary for positive change, along with empathy and genuineness (congruence). According to the Rogerss theory, mental illness is often caused by the absence of love or by a defective kind of love that the client received as a child. By showing the client unconditional positive regard and acceptance, the therapist is providing the best poss ible conditions for personal growth to the client. (Campbell, 1985) One regards ‘each aspect of the client’s experience as being part of that client . (Bozarth, 2001) While all four of the historical forces have contributed to the development of American psychology and psychological theories, I believe it is the cognitive behavorial and existentialistic ideologies such as the theories of Ellis’ (REBT) and Rogers’(UPR) that have had the greatest impact on psychotherapy and its multi-cultural applications . I can honestly say that my views and opinions have been changed by the knowledge I have gained from the History and Systems class also known as psychology 308. From a cultural perspective  I have always felt I belonged to two different worlds. I was born in Kentucky and raised in a very conservative , narrow-minded community. The predominant school of thought was very racist. My ethnic heritage is Scotch-Irish and I was taught as a child to have a dislike for those who were not like me. Imagine, if you will, the conflict I felt as a child who played with dolls, hated baseball, and had an attraction to members of my sex. Researchin g the different theoritical orientations in psychology has been an extremely enlightening experience. While I do not profess to be of any religious or spiritual mindset, I have developed an interest in the Buddhist approach of self-acceptance to life. I am almost 46 years old and I have made my share of mistakes along the way. Self acceptance has always been something I have struggled with. Dr. Ellis’ REBT and Buddhist psychological approaches have given me the tools to take a greater look at myself and to be okay with what I see. I intend to be an advocate for those people like myself who have felt cheated by the cultural values or norms put forth by American psychological culture. Times may be changing, but in my opinion not fast enough. As we move to a more culturally diverse nation I hope that the plight of gay, lesbian, and transgendered persons will be considered in the greater development of multi-cultural psychology. Brook, J. S., Whiteman, M. (2008). Onset of adolescent drinking: a longitudinal study of intrapersonal and interpersonal antecedents. Bibliography Bozarth, J. (2001). Unconditional Positive Regard (Rogers Therapeutic Conditions Evolution Theory Practice. Pccs Books. Campbell, P. A. (1985). Bio-spirituality: focusing as a way to grow. Loyola University Press. Ellis, A. (1994). Reason and Emotion in Psychotherapy . Birch Lane . Hanh, T. N. (1999). The Heart of the Buddhas Teaching:Transforming Suffering into Peace, Joy, and Liberation . Broadway Books. M.G.T. Kwee, K. G. (2006). Horizons in Buddhist Psychology: Practice, Research Theory,. Chagrin Falls : Taos Institute Publications. maslow, A. (1968). Toward a Psychology of Being. New York: Princeton. Tsering, G. T. ( 2006). Buddhist Psychology: The Foundation of Buddhist Thought.

Wednesday, August 21, 2019

Learning Skills for Open and Distance Learners

Learning Skills for Open and Distance Learners 1.0 INTRODUCTION Online learning is new type of further studies offer by higher academic learning around the world. Before higher academic learning institution offer this style of learning method, traditional learning such as class room meeting or face to face learning, part time learning and distance learning was successfully born professional worker and great management leader. The demanding of the professional skill worker increase severely every years and the awareness about further studies by people specially adult make higher academic learning institution think the new way to support and give a opportunity to adult people to upgrade their academic qualification and upgrade their living. The academic professional every day burn their midnight oil to think the new kind of learning to fulfill this adult people need and perform the best practice of learning to suit with adult people lifestyle mostly working and having own family. These academic professional lastly come out a brilliant ideas to support new learning method for adult people. The Online Learning was introduced to the open market and the result is sufficiently encouraging adult people to further their study. According to Tham (2004), learner who evolved from distance learning and traditional face to face classroom now change to online learning method. Although this new learning method is design to suit adult learners, adult learners still have a problem especially in the first year of beginning the online learners. In this paper we will discuss about the problem faced by beginning online learners and typically try to solve it accordingly support from professional thinker facts. 2.0 BACKGROUND OF LEARNING ONLINE In this Information Era, Computers and Internet is very important media for channeling information. Its means Online Learning method use this type of media for learning process. Academic institution use computers and internet and adding this media to create a study environmental class for their online students. This situation is look like an invisible classroom to the online student (Tham, 2004). According to Chen Sun (2008) to develop an integrate online learning module, it involve six dimension criteria. To develop online method criteria, Learners, Instructors, Design, Technology, Environment and Course mix together to fulfill Online Learning methodology. Now we want to focusing one of six criteria that will be discussed with deeper and examine. Although the all six criteria important in online learning, students capability itself to separate the five criteria that need to be prioritized. Be a beginner in online learners is a challenging because learners are compulsory to learn by itself. According to Ash (2010), online learner only spends 2 (two) hours and 15 minutes for lesson in a classroom per week and spends almost the rest of lesson virtually from home. It make sense from Tham (2004) statement invisible classroom. Make your own learning classroom at home using the technology and educational material provide from academic institution. 3.0 FINDING PROBLEM VERSUS SOLVE PROBLEM Be a beginners of online learners is very challenging decision. Mostly online learners are adult working and own family person. They must add more burden thing in their live. The flexible time is the major fact adult people attract to use online learning to fulfill their dream to grab degree or master scroll, but as online learners you must deduct time for learning, working, social, family and resting yourself. Someone said financial and working condition also the problem faced by beginner online learners. These problems are happen actually before becoming online learners. These people will think and doing some research before choose online learning as their learning study method for further their education. They must settle all financial and working condition matter before enrolls with academic institution. Now we will discuss about the problem after student enroll to academic institution and becoming online learners. The most important problem faced by beginning online learners is their mentality issue. According to Combes,(2006). The major issue in mentality problem of beginning in online learners is lack of mentality. He find out is four (4) issues on mental problems which occurred to online learners namely most isolation and lack of identity, lack of motivation, lack of confidence and anxiety. 3.1 Isolation and lack of identity This mental issue about this mentality problem is the feeling inside when online student start enroll as online learners. When online learners start their learning process at home, actually their friend only books and personal computer in front it. What feeling inside online learners thats time is loneliness. According to Pond (1998) loneliness define as an enduring condition of emotional distress that arises when a person feels estranged from, misunderstood, or rejected by others and or lacks appropriate social patterns for desired activities, particularly activities that provide a sense of social integration and opportunities for emotional intimacy. Online learners will not have immediate and fast access to lectures and peers when learning activities begin. No fast respond about their difficulty make online learners unhappy and the social time with their colleague also reduce due to increase time for spending in learning make loneliness or feel of isolation becoming worst. Now we l earn how to overcome this problem related to online learners. According to Rosenblit, (2005) Academic institution must providing good interaction between online learners and tutor. Active peer greatly needed to always contact with online learners to help among themselves. What is most important once is every online learner should give information on this problem and understand that state and knowledge to resolve. Online learners also be encouraged to hold grouped discussion once in a while with peer to share knowledge and their problem and dont keep your problem alone. 3.2 Lack of motivation Motivation is important mental support to achieve high quality as online learners. Motivation is consist of psychological, biological, social and cognitive cause direct behavior (Fulmer 2009). Motivation is spirit hidden inside a person. Online learner with week motivation will cause him unenterprising, often absent from class and no planning in manage self learning. Lack of motivation is a serious problem for online learners and the percentage to fail is highest. How to overcome this problem? To motivate online learners is not same with traditional learners. It because Online learners almost an adult person. They have be different approach or strategy to motivate them. They are five step to motivate learners. 3.2.1. Reward myself People always get motivated by rewarding something. Setup a goal for yourself and reward yourself. Example, if I can finish this semester, My family and I will take a vacation to Manchester, England. 3.2.2. Make sure my course has real value Before you start learning, make sure you choose course can reward you something very valuable. Example, if Im get P.H.D, all my article and books will be recognize and the publishing company will offer me as a Chief Editor. 3.2.3. Help me perform better You must relate what you learn with your working environment. If you choose course similarly with your real working environment, it make you perform better in your studies and your job. 3.2.4. Set clear expectation for the course You must setup your mind, the course that you learn will give you new information and you will use that information later. These tips also need help by a tutor to explain what you will learn and achieves after finish it. 3.2.5. Tell me if Im wrong These tips also need tutor fully cooperation. You may ask your tutor to tell you if you do something wrong with your quiz, assignment or in learning process. Sometimes adult learners also need a little attention to keep them continually motivate. They technique and method to criticize online learner must be suitable. Offences criticize online learner will probably become worst. 3.3 Lack of confidence Lack of confidence also an issue for online learners. 47.5% citing lack of confidence when they use internet for their study (Combes 2006). This student actually want more practical assistance when enroll to the academic institution. Confident means full trusts, believe in one self, abilities and reliability to think. People always said, if we have confidents, we have ability to success. How to drive up confident? They have five (5) tips to overcome this problem. 3.3.1. Find support You have your own family and you need them now to support and understand you as online learners. Your also can find support around your peer and friend. All this combination of support can drive up your confidence back. 3.3.2. Apply your skill You are online learners because you are working person. Try apply your working skill to your learning environment. If you working as a shift hours, it means you can work in the morning, afternoon and night. So you can take this working environment to your learning environment. You can do learning process in the morning, afternoon or at night. That is your advantage! 3.3.3. Set reasonable goal You must set a goal for what u doing. If you now as online learners, you must set a goal to get a diploma, degree, master or P.H.D. whatever happen. Write your goal in a white board, working table or else where that easy to you to see. 3.3.4 Develop a routine You must develop your own time management planner to arrange your study time, working time, family and resting hour. If you set a daily planner to manage your activities, please stick on it. Try to arrange activities at the same time everyday, because if you do the same thing and the same time everyday, lastly it become your routine. 3.3.5 Never stop dreaming Dreaming is not a good thinker but sometime dreaming is good depends on the situation. Dreaming to be success is good thinker but it must follow with effort. With a high passion and never stop effort is the key to success. Online learning must dream to grab a scroll of their certificate on the stage of the high profile convocation event everyday. 3.4 Anxiety Anxiety is feeling inside online learners if they dont well prepare. 51% experiencing anxiety when using the internet for study (combes 2006). The impact of anxiety always happen at younger online learners. According to wikipedia, Anxiety define as psychological state characterized by somatic, emotional, cognitive and behavioral components either the absence or presence of psychological stress, feeling of fear, worry, uneasiness and dread. In learner concept Anxiety is define as psychological and physical response to treat a self concept characterized by subjective, consciously perceived feelings of tension( Vitasari 2010). According to Mauri (1992), the major problem of anxiety is panic situation. How to overcome panic situation? According to Gard (1999), panic must be handles carefully before it become panic attack. These is are three (3) tips to overcome this problem. 3.4.1 Know first before deal That mean learners must know randomly about the course and the syllabus before attending to face to face meeting. Example, work seeker also must know about the company history first before attend an interview. 3.4.2 Always relax Learn to relax yourself when panic situation appear. Take a deep breath and exhale with your mouth slowly. Try to calm down and try to think creatively to overcome that situation. Get help if you cannot handle that situation by yourself. 3.4.3 Believe yours religious Always pray to avoid you from panic situation. We believe all religious have their own way to overcome this panic situation. 4.0 CONCLUSION They are many problem faced by beginner online learners. Financial and Working matter are not relevant problem by beginner online learners. The major problem is mentality issue. Isolation and lack of identity, lack of motivation, lack of confidence and anxiety are the major problem will faced all beginner online learners. To overcome isolation and lack of identity, academic institution must providing good interaction between online learners and tutors and active peer. Five (5) tips like reward myself, make sure my course has real value, help me perform better, set clear expectation for the course and tell me if Im wrong are the tips to overcome lack of motivation problem. They have also five (5) tips to overcome lack of confidence. Find support, apply your skill, set reasonable goal, develop a routine and never stop dreaming is the key to avoid lack of confidence. Anxiety are similarly to panic situation. Three (3) tips to overcome this problem are know first before deal, always relax and believe yours religious. 5.0 REFERENCES Kim, K.J. (2009). Motivational challenges of adult learners in self-directed E-Learning.  Journal of Interactive Learning Research, 20(3), 317. Retrieved from  proquest.com (OUM Digital Library) Ash, K. (2010). Blended learning seeks the right mix: School combine virtual and face-to-face teachers to meet student needs. Education Week, 30(4), 8. Retrieved from  Proquest.com. (OUM Digital Library) Tham, C.M, Werner, J.M. (2004). Designing and evaluating E-learning in higher  education: A review and recommendations. Journal of Leadership   Organizational Studies, 11(2), 15. Retrieved from proquest.com (OUM Digital  Library) Combes, B., Anderson, K. (2006). Supporting first year E-learners in courses for the  information professions. Journal of Education for Library and Information  Science, 47(4), 259. Retrieved from proquest.com (OUM Digital Library) Pond, S.S.C. (1998). Acceptance and belonging the promotion of acceptance and  belonging within group art therapy: A study of two lonely third grade students.  American Journal of Art Therapy, 36(3), 81. Retrieved from proquest.com  (OUM Digital Library) Rosenblit, S.G. (2005). Eight paradoxes in the implementation process of E-learning in  higher education. Higher Education Policy, 18(1), 5. Retrieved from  Proquest.com (OUM Digital Library) Fulmer S.M., Frijters, J.C. (2009). A review of self-report and alternative approaches in  measurement of student motivation. Educational Psychology Review, 21(3), 219.  Retrieved from proquest.com (OUM Digital Library) Vitasari. P., Wahab, M.N.A., Othman, A., Awang, M.G. (2010). A research for  identifying study anxiety sources among university students. International  Education Studies, 3(2), 189. Retrieved from proquest.com ( OUM Digital  Library) Mauri, M., Sarno, N., Rossi, V. M., Armani, A., Zambotto, S., Cassano, G. B., Akiskal,  H.S. (1992). Personality disorder associated with generalized anxiety, panic, and  Recurrent depressive disorders. Journal of Personality Disorders, 6(2), 162.  Retrieved from proquest.com (OUM Digital Library) Gard, C.J. (1999, coping with the fear of fear. Current Health 2, 25(5), 22.Retrieved from  Proquest.com (OUM Digital Library) Pei-Chen Sun, Ray J. Tsai, Glenn Finger, Yueh-Yang Chen, Dowmin Yeh (2008).  Computers Education 50(4) 1183-1202. Retrieved from www. Sciencedirect.com The Rapid e learning blog. Retrieved from www.articulate.com/rapid-elearning/motivate-your-learners-with-these-5-simple-tips/ Anxiety. Retrieved from http://en.wikipedia.org/wiki/Anxiety

Tuesday, August 20, 2019

MAMLD1 Mutation and Phenotypes of Hypospadias

MAMLD1 Mutation and Phenotypes of Hypospadias The relationship between clinical phenotypes and mutations of MAMLD1 in children with hypospadias Yong-fen Lv, Lu-lu Cui, Pin Li* Department of Endocrinology, Shanghais Children Hospital, Shanghai Jiaotong University Acknowledgements: The work was financially supported by the key project of Shanghai municipal health bureau (2011111), youth project of Shanghai municipal health bureauà ¯Ã‚ ¼Ã…’major issue subprojects of Shanghai science and technology commission (12411952408), Yangtze river delta research project of Shanghai science and technology commission (13495810300). Abstract Purpose: To verify the relationship between clinical phenotypes of hypospadias and mutations of MAMLD1. Methods: Seventy-two patients were diagnosed to be hypospadias in department of endocrinology and department of urinary surgery in our hospital. Among all the patients, 69 were with normal karyotype and enrolled as the studied group. Fifty healthy boys were employed as the controls. Peripheral Blood were collected for DNA extraction. For the studied group, PCR primer was designed and direct sequencing was performed for screening for MAMLD1 mutations in six coding exons and the flanking region. Those mutated exons were examined for the control group. Results: Thirty-five of all the 72 patients (48.6 %) were isolated hypospadias. The other 37 cases (51.4%) were complicated by other genitourinary system malformations, including 12 cases with micropenis and/or underdeveloped testicles. Abnormal karyotype was identified in 3 patients, and all were karyotype as 46, XX (SRY+ in 1 case and SRY- in 2 cases). Six types of MAMLD1 mutations were detected in exon 2, 3, 5, 7 in studied group, including c.5A>G (p.D2G), IVS4-364C/A, c.1910A>Gà ¯Ã‚ ¼Ã‹â€ p.N637S), c.2208T>C, c.2227 G>A (p.E742K) and IVS8-144C/T. All were single nucleotide polymorphism except c.5A>G (p.D2G), a newly discovered point mutation. The frequency of IVS4-364C/A was significantly different between patients and controls, and it was also significantly different between patients with and without micropenis and/or underdeveloped testicles. Conclusion: Chromosome abnormality is not the leading cause of other genitourinary system malformations complicated with hypospadias. Mutations of MAMLD1 maybe closely related to hypospadias in Chinese. c.5Aà ¯Ã‚ ¼Ã… ¾Gà ¯Ã‚ ¼Ã‹â€ p.D2Gà ¯Ã‚ ¼Ã¢â‚¬ °is the newly discovered point mutation in this work. IVS4-364C/A is associated with underdeveloped testicles and/or micropenis in hypospadias patients. Introduction Hypospadias is one of the most common congenital genitourinary system malformations in males, with incidence 1†°Ãƒ ¯Ã‚ ½Ã… ¾1%. As one of the Juvenile-types of testicular dysgenesis syndrome,(1-3) the prevalence of hypospadias is obviously increasing in these years. From 1987 to 2001, the prevalence rate was doubly increased in China.(4) Hypospadias will lead to different degrees of genital malformation, and the clinical phenotypes vary when with other complications. For instance, besides the general signs of hypospadias, e.g., ectopic ureteral orifice, phallocampsis, redundant dorsal prepuce, etc, the patient may be also suffered from other malformations including penoscrotal transposition, cryptorchidism, hydrocele, oblique inguinal hernia, micropenis and underdeveloped testicles. Hypospadias is a complicated disease due to various causes. The causes of most cases are not able to be verified, especially for those mild cases. For these cases, environmental factors, endocrine fa ctors and abnormal gene expression may be the leading causes.(5) The sex differentiation of males is a continuous series of processes related on the balancing and interaction of various genes like SRY, WTl, ATF3, SF-1, etc. MAMLD1, which is previously called chromosome X open reading frame6 (Cxorf6), is the important candidate gene widely studied recently. This gene is located in Xq28,(6,7) with molecular length of 157898 bp and containing 8 exons, among which exon 2, 3, 4, 5, 6, 7 are coding exons. MAMLD1 is initially detected in patients with X-linked myotubular myopathy. The reproductive systems of patients are normally developed with mutations in Myotubularin MTM-1, while different degrees of malformations occur in cases with deletion of MTM1 gene.(8-11) The subsequent experiments indicated that, for patients with 46, XY disorder of sex development (DSD), except MAMLD1, no other candidate genes were found in the deletion region. These results indicate that MAMLD1 is the perfect candidate gene for the study of 46, XY DSD, especially for hypospa dias. This work aimed to evaluate the mutations of MAMLD1 and clinical phenotypes in children with hypospadias in China, and thus to illustrate the role of MAMLD1 mutation in hypospadias. Methods Patients Seventy-two children with hypospadias admitted to Shanghai Childrens Hospital Affiliated to Jiaotong University from March 2011 to December 2012 were enrolled in this study. Definite diagnosis was based on the clinical signs, and patients with adrenogenital syndrome were excluded through clinical examination. Clinical examination Clinical survey was performed including patient’s complain, present medical history, past medical history, personal history, family history, birth history, mother’s medical history in pregnancy, previous exposure to environmental pollution, etc. Physical examination was performed to measure the hight, weight, heart rate, blood pressure and the status of gonad development, etc. For adolescent, the development of secondary sexual characteristics was also assessed. Regular auxiliary examinations were performed including blood and urine routine test, biochemistry test, gonadal hormone level, adrenal cortex function and abdominal ultrasound exam, etc. Karyotype analysis and detection of SRY gene Lymphocytes were isolated from peripheral blood of patients, cultured and smeared on slides, and G-bands were produced by treatment with trypsin. Thirty split-phases were selected for each case, and karyotype analysis was performed according to ISCN-1995. SRY gene detection was performed for all the patients. Screening for MAMLD1 mutations The gene sequence of MAMLDI was obtained from National Center for Biotechnology Information (NCBI), which was the same as obtained from Ensembl Genome Browser: NC_000023.10 (NCBI) versus ENSG00000013619 (Ensembl release 70-January 2013). Primers were designed for the coding exon 2, 3, 4, 5, 6, 7 of MAMLD1. DNA extraction was performed using TIANamp Blood DNA Kit (TIANGEN Biotech (Beijing) Co., Ltd, China) and purity test was done. Ploymerase chain reaction (PCR) was performed with use of LONGgene A300 PCR and Premix Ex Taq Version2.0 (TaKaRa D332A), GC buffer (TaKaRa DRR20GC1) and rTag (TaKaRa DR001BM), 35 cycles of denaturation at 94à ¢Ã¢â‚¬Å¾Ã†â€™ for 30 seconds,extension at 72à ¢Ã¢â‚¬Å¾Ã†â€™ for 60 seconds. Mutations were identified in the six coding exons and flanking regions of MAMLD1, and those mutated exons were examined for the control group. Statistical analysis The SPSS 18 software was used for statistical evaluation. Chi-square test was used to compare the two groups, frequency of single nucleotide polymorphism between the two groups was analyzed using Fisher Exact test, and differences were considered statistically significant when the p-value was G (p.D2G), IVS4-364C/A (rs1209024), c.1910A>G (p.N637S), c.2208T>C, c.2227 G>A (p.E742K, rs5925166) and IVS8-144C/T (rs658748). Two types of mutations were detected in exon 5 and 7 in all healthy controls, including c.1910 A>G (p.N637S, rs2073043) and c.2208T>C. Among all the mutations, c.5A>G (p.D2G) was a newly discovered point mutation, others were all single nucleotide polymorphism. The studied group compared to the control group, the frequency analyzed by Fisher Exact test, the P value for IVS4-364C/A, c.1910A>G (p.N637S), c.2208T>C, c.2227 G>A (p.E742K) and IVS8-144C/T were 0.002, 0.638, 0.362, 1 and 0.509 respectively. Therefore, the frequency of IVS8-144C/T was significantly different be tween the two groups, and the frequency of the other 4 SNPs were not significantly different between the two groups. Relationship between mutations of MAMLD1 and clinical phenotypes of hypospadias One case with c.5A>G (p.D2G) was isolated hypospadias, the urethral opening position was located at the middle segment of penis. Due to the limited number of mutation cases, the sample size should be increased to study the relationship between c.5A>G (p.D2G) and phenotypes of hypospadias. Analyzed by Chi-squared test with Yates continuity correction, the frequency of IVS4-364C/A was significantly different between patients with and without micropenis and/or underdeveloped testicles (p=0.001). Discussion Chromosome abnormality and karyotype change is one of the causes of hypospadias. Till now, ten types of chromosome abnormalities were confirmed involving chromosome 1, 4, 6, 8, 11, 13 19, 20, 21, X, Y, etc. In the studied 72 patients, abnormal karyotype was identified in 3 patients, and all were karyotype as 46, XX (SRY+ in 1 case and SRY- in 2 cases). For these three patients, uterus and ovary were not found through the laparoscopic exploration. Therefore, they were diagnosed to be 46, XX male sex reversal syndrome. Karyotype analysis is important for hypospadias patients with sex reversal syndrome in exploring candidate gene and pathogenesis, in clinical diagnosis as well as in making therapeutic plan. However, there are only 3 cases with karyotype abnormality in the 72 patients studied, which means chromosome abnormality is not the leading cause of hypospadias. MAMLD1 is initially detected in patients with X-linked myotubular myopathy. The reproductive systems of patients are normally developed with mutations in Myotubularin MTM-1, while different degrees of malformations occur in cases with deletion of MTM1 gene.(8-11) Except MAMLD1, no other candidate genes were found in the deletion region. These results indicate that MAMLD1 is the perfect candidate gene for the study of 46, XY DSD, especially for hypospadias. In the works of Fukami et al., three nonsense mutations were detected, i.e., p.E124X, p.Q197X and p.R653X, in 4 XY DSD cases, involving micropenis and hypospadias with urethral opening position located on scrotum and the joint at penis and scrotum.(12) Kalfa et al. have studied the mutations of MAMLD1 in hypospadias patients and discovered 3 mutations, including p.V432A, p.E109fsX121 and P.531ins3Q, and they proposed that 10 percent of all the severe hypospadias cases was caused by mutations of MAMLD1.(13) In the study of Chen et al., three mutations of MAMLD1 were discovered, i.e., p.Q529K, p.D686D and noncoding region c.2065+8a>t, in 99 Swedish with hypospadias.(14) However, this is not the case in China. Qian et al. have studied the mutations of MAMLD1 in 100 cases of isolated hypospadias,(15) where 200 healthy participants were randomly selected as control. In their work, two point mutations, c.1699C>T and c.1985A>G, were detected and all were SNPs, and statistical analysis revea led that MAMLD1 is not the candidate gene for isolated hypospadias in China. The different results may be due to the different inclusion criteria of studied population between China and abroad, i.e., the studied populations of foreign works were mostly composed by hypospadias cases complicated by other genitourinary system malformations, including gonadal dysgenesis, while mostly isolated hypospadias cases were selected in the works of Chinese. In this study, a new point mutation c.5A>G was detected in exon 2 of one patient, and this mutation was not found in controls. The mutation makes the second amino acid position, originally the hydrophilic negatively charged aspartic acid, substituted by a neutrally charged glycine. For various species, the second amino acid position in exon 2 of MAMLD1 is highly conserved, and analyzed via polyphen, the mutation c.5A>G (p.D2G) of MAMLD1 is predicted to be probably damaging with a score of 0.996 from HumDiv and 0.993 from HunVar, which indicates that c.5A>G (p.D2G) is highly related to hypospadias. SIFT predicts that the mutation can affect protein function, since there is no protein diversity on the site (supplementary figure 20). The case with c.5Aà ¯Ã‚ ¼Ã… ¾G was isolated hypospadias, and the urethral opening was located in the middle segment of penis. A big sample size and the information of the exact protein function are required to elucidate whether c.5A>G (p.D2G) of MAMLD1 is the cause of isolated hypospadias and its role in human sexual differentiation. The meaningful SNP detected in this work is the full mutation in introns close to exon 3, i.e., IVS4-364C/A (rs1209024), in 12 patients, which is not found in controls. The 12 cases including 2 cases with anterior hypospadias, 9 cases middle urethral openings and 1 case posterior urethral opening. Among all the 12 patients, 6 were complicated by 2 other malformations, 8 cases were complicated by micropenis and/or underdeveloped testicles. Generally, introns are non-coding sections of a gene, which are removed before the mature mRNA can be transported, thus do not exist in the mRNA sequence. However, there may be several mini genes in some introns, the so called genes-within-genes. The frequency of IVS4-364C/A was significantly different between patients and controls, and it was also significantly different between patients with and without micropenis and/or underdeveloped testicles. Therefore, two possibilities could be speculated, the first is that there may be coding sequence relat ed to micropenis and/or underdeveloped testicles in the introns close to exon 3 of MAMLD1, the second is that the mutation could affect mRNA shear mode, thus lead to the change of protein function. Next step of our study plan is to verify whether the mutation could affect mRNA shear mode through reverse transcription, amplification and sequencing of extracted mRNA. References 1. Skakkebaek NE, Rajpert-De ME, Main KM. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod 2001;16:972-8. 2. Sharpe RM. Pathways of endocrine disruption during male sexual differentiation and masculinization. Best Pract Res Clin Endocrinol Metab 2006;20:91-110. 3. Sharpe RM, Skakkebaek NE. Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertil Steril 2008;89(2 Suppl):e33-8. 4. Wu YQ, Dai L, Wang YP, Liang J, Zhu J, Wu DS. Secular Trends of Hypospadias in Chinese Perinatals. J Sichuan Univ (Med Sci Edi) 2005;36:274-6. 5. Liang WQ, Ji CY, Zhang JM, et al. The correlation between the type of hypospadias and external genital system malformations. Chin J Urol 2011;32:126-9. 6. Laporte J, Kioschis P, Hu LJ, et al. Cloning and char acterization of an alternatively spliced gene in proximal Xq28 deleted in two patients with intersexual genitalia and myotubular myopathy. Genomics 1997;41:458–62. 7. Laporte J, Guiraud-Chaumeil C, Vincent MC, et al. Mutations in the MTM1 gene implicated in X-linkedmyotubular myopathy. ENMC International Consortium on Myotubular Myopathy. European NeuroMuscular Center. Hum Mol Genet 1997;6:1505-11. 8. Bartsch O, Kress W, Wagner A, et al. The novelcontiguous gene syndrome of myotubular myopathy(MTM1), male hypogenitalism and deletion in Xq28: report of the first familial case. Cytogenet Cell Genet 1999;85:310-4. 9. Bates PA, Kelley LA, MacCallum RM, et al. Enhancement of protein modeling by human intervention inapplying the automatic programs 3D-JIGSAW and3D-PSSM. Proteins 2001;S5(Suppl 5):39-46. 10. Biancalana V, Caron O, Gallati S, et al. Characterisation of mutations in 77 patients with X-linked myotubular myopathy, including a family with a very mild phenotype. Hum Genet 2003;112:135-42. 11. Hu LJ, Laporte J, Kress W, et al. Deletions in Xq28 in two boys with myotubular myopathy and abnormal genital development define a new contiguous gene syndrome in a 430 kb region. Hum Mol Genet 1996;5:139-43. 12. Fukami M, Wada Y, Miyabayashi K, et al. CXorf6 is a causative gene for hypospadias. Nat Genet 2006;38:1369-71. 13. Kalfa N, Liu B, Klein O, et al. Mutations of CXorf6 are associated with arrange of severities of hypospadias. Eur J Endocrinol 2008;159:453-8. 14. Chen Y, Thai HT, Lundin J, et al. Mutational study of the MAMLD1-gene in hypospadias. Eur J Med Genet 2010;53:122-6. 15. Qian C, Lin HW, Sun P, et al. Research of MAMLD1 gene in Hypospadias. J Clin Pediatr Surg 2012;11:106-11. Figure Legends Figure 1. Mutations of MAMLD1, the number represents the exon serial number, the black area represents the coding region. Table 1à ¯Ã‚ ¼Ã… ½Clinic phenotypes of 72 patients with hypospadias Table 2. Patients complicated by other genitourinary system malformations Table 3. Mutations of MAMLD1 gene screened in patients and controls

Monday, August 19, 2019

Macbeths Queen Essay -- Macbeth essays

Macbeth's Queen      Ã‚   There are two main characters in William Shakespeare's Macbeth, one of which is Lady Macbeth. Let us in this paper study her character in detail.    Blanche Coles states in Shakespeare's Four Giants evaluates the character of Lady Macbeth:    A woman who could speak as Lady Macbeth does, who could call upon the spirits that tend on mortal thoughts to unsex her and fell her from head to foot full of direct cruelty, who could entreat these same spirits to stop all avenues of remorse so that no compunctions of conscience will interfere with the carrying out of her purpose, who could call upon the night to wrap itself in the murkiest, gloomiest smoke of hell in order to hide, even from the keen knife she would use, the wound she would make when she herself stabs the sleeping King, such a terrible, frightful woman would not scruple at telling a little wife-to-husband lie to accomplish her purpose. (52)    In Everybody's Shakespeare: Reflections Chiefly on the Tragedies, Maynard Mack shows how Lady Macbeth complements her husband:    Her fall is instantaneous, even eager, like Eve's in Paradise Lost; his is gradual and reluctant, like Adam's. She needs only her husband's letter about the weyard sisters' prophecy to precipitate her resolve to kill Duncan. Within an instant she is inviting murderous spirits to unsex her, fill her with cruelty, thicken her blood, convert her mother's milk to gall, and darken the world "That my keen knife see not the wound it makes" (1.5.50). Macbeth, in contrast, vacillates. The images of the deed that possess him simultaneously repel him (1.3.130, 1.7.1) When she proposes Duncan's murder, he temporizes: "We will speak further" (1.5.69). (189)    ... ...Blakemore Evans. Boston: Houghton Mifflin Company, 1972.    Knights, L.C. "Macbeth." Shakespeare: The Tragedies. A Collectiion of Critical Essays. Alfred Harbage, ed. Englewwod Cliffs, NJ: Prentice-Hall, Inc., 1964.    Mack, Maynard. Everybody's Shakespeare: Reflections Chiefly on the Tragedies. Lincoln, NB: University of Nebraska Press, 1993.    Shakespeare, William. The Tragedy of Macbeth. http://chemicool.com/Shakespeare/macbeth/full.html, no lin.    Siddons, Sarah. "Memoranda: Remarks on the Character of Lady Macbeth." The Life of Mrs. Siddons. Thomas Campbell. London: Effingham Wilson, 1834. Rpt. in Women Reading Shakespeare 1660-1900. Ann Thompson and Sasha Roberts, eds. Manchester, UK: Manchester University Press, 1997.    Wilson, H. S. On the Design of Shakespearean Tragedy. Toronto, Canada: University of Toronto Press, 1957.

Sunday, August 18, 2019

College Party Life Essay -- Personal Narrative Writing

College Party Life College parties at JMU, both on campus and off-specifically off-campus, may seem a mish mash of little planning, teenage hormones, beer induced chaos and the new found freedom, for some at least, from ones parents. This however is just a superficial observation. The college party scene at JMU is highly ritualized, even regimented. According to your social status, the people you know, activities you are involved (mainly sports), and the way you look, act, and dress all affect your experience of a college party. The universal party night for students is Saturday, JMU students being no exception. For most students at Madison, the week is wrought with worry and toil over books, notes, classes, and exams. One reason to explain why parties sometimes get the way they do, is that Saturday night for students is a catharsis, all the pressure that students feel can be forgotten and they can act freely in what they feel is a worry-free environment. For me, Saturday Party Time (SPT) starts around anywhere from 8 to 10 that night. The time depends on what kind of party is planned, a very large dance party, or a smaller quieter get-together of some member of the Cross Country Team. In order to get to where I always party, Pheasant Run, I have to take the bus. This is where the night really starts. If I take the bus at 8, I am usually one of only a handful of people on the bus. Usually I go at 10, though, and it is quite evident that a party is going on somewhere. By ten Saturday night there are usually over a hundred students waiting at the bus stop. I don’t even bother dressing up; I prefer jeans and a tee-shirt with a pair of worn sneakers and a hoody with a hole in the back of it. I am no... ...d gender status (Robbins 2002: 175-78). Females dress in revealing ways so as to become more desirable, thus they not only spend an inordinate amount of time choosing clothing, but also in person grooming and accessorizing. In this way, females present themselves as targets, to be picked up, taken, and/or dominated by the males. This is also reinforced by the method of dancing that is currently popular among party -goers. The positioning of the male and female, in which the male puts his hands on the female and is able to control her movements with his body shows the acceptance of male dominance and the subordination of females, at least in sexual and dating matters. This is an example of social stratification by gender (Robbins 2002: 216). Women are made to do an inordinate amount of work and preparation for Saturday night, only to be taken control of by males.

Saturday, August 17, 2019

Chemalite, Inc (B)

Problem Set #2: Chemalite Case 1. Record the effects of Chemalite’s 1991 events on the BSE worksheet Cash Flow type (O, I, F) Event Cash A/R 375,000 F P1 (7,500) I P2 P3 (62,500) I (75,000) O P4 230,000 Inventory Patent Cap. Exp. PPE 125,000 7,500 62,500 125,000 7,500 62,500 Notes Pay Paid in Capital RE 500,000 RE Explanation 75,000 75,000 – 500,000 – Balance Sheet O O O O O O I F – T1 T2 T3 T4 T5. 1 T5. 2 T6 T7. 1 T7. 2 O1 O2 O3 O4 O5 Total 23,750) 685,000 69,500 (175,000) (22,500) (350,000) (80,000) (150,000) 50,000 (50,750) (23,750) R&D Expense 754,500 Revenue 175,000 (22,500) Adv. Expense 350,000 (80,000) Admin Expenses 150,000 50,000 (50,000) F (545,000) (25,000) (10,625) O (750) (545,000) (25,000) (10,625) 500,000 Interest Expense Inv. Adjustment Amort. Expense Depr. Expense 113,000 69,500 55,000 100,000 7,500 201,875 – 46,875 Balance Sheet 15. 515 Fall 2003 Session 1 Problem Set #2: Chemalite Case 3. Balance Sheet (6/31/91): Assets Cash Accounts Receivable Inventories Total Current Assets Property, Plant, & Equipment Other (Capitalized Start-up Expenses) Patent Total Assets Liabilities and Stockholders' Equity Common Stock Retained earnings Total Liabilities and SE 230,000 75,000 305,000 62,500 7,500 125,000 500,000 500,000 500,000 15. 515 Fall 2003 Session 1 Problem Set #2: Chemalite Case 3. Income Statement (For 6 months June 30, 1991): Revenue Costs and Expenses Advertising Administration Manufacturing costs Raw materials R Interest Depreciation Amortization of patent – Net Income – 15. 515 Fall 2003 Session 1 Problem Set #2: Chemalite Case 3. Direct Statement of Cash Flows (6 months ended June 30, 1991): Cash provided (used) by operating activities Received from customers Paid for inventory Paid for advertising Paid for manufacturing costs Paid for administration Paid for interest Paid for R expenses Cash provided (used) by investing activities Start-up expenses Purchase of PP (75,000) (75,000) (7,500) (62,500) (70,000) Cash provided (used) by financing activities Cash from stock issuance 75,000 375,000 Increase (decrease) in cash balance Beginning cash balance Ending cash balance 230,000 230,000 15. 515 Fall 2003 Session 1 Problem Set #2: Chemalite Case 3. Balance Sheet (December 31, 1991): Assets Cash Accounts Receivable Inventories Total Current Assets Property, Plant, & Equipment Other (Capitalized Start-up Expenses) Patent Total Assets Liabilities and Stockholders' Equity Common Stock Retained earnings Total Liabilities and SE 113,000 69,500 55,000 237,500 201,875 7,500 100,000 546,875 00,000 46,875 546,875 15. 515 Fall 2003 Session 1 Problem Set #2: Chemalite Case 3. Income Statement (Six months ended December 31, 1991): Revenue Costs and Expenses Advertising Administration Manufacturing costs Raw materials R&D Interest Depreciation Amortization of patent 754,500 22,500 80,000 350,000 195,000 23,750 750 10,625 25,000 707,625 Net Income 46,875 15. 515 Fall 20 03 Session 1 Problem Set #2: Chemalite Case 3. Direct Statement of Cash Flows (For 6 months ended Dec. 1, 1991): Cash provided (used) by operating activities Received from customers Paid for inventory Paid for advertising Paid for manufacturing costs Paid for administration Paid for interest Paid for R&D expenses Cash provided (used) by investing activities Start-up expenses Purchase of PP&E 685,000 (175,000) (22,500) (350,000) (80,000) (750) (23,750) 33,000 (150,000) (150,000) Cash provided (used) by financing activities Cash from stock issuance – Increase (decrease) in cash balance Beginning cash balance Ending cash balance (117,000) 230,000 113,000 15. 515 Fall 2003 Session 1

Friday, August 16, 2019

Quiz on Human Pathophysiology

This assignment is worth 40 points. Please make sure you have answered all questions prior to submitting. Once you click the submit button, you will not be able to return. Question 1 of A 9-year-old patient Is admitted to a pediatric unit with Dutchmen muscular dystrophy. Which of the following traits was this condition Inherited from? Sex-linked dominant Excellences Sex-limited Sex-linked recessive 2 of 40 A 70-year-old male with chronic renal failure presents with edema. Which of the following is the most likely cause of this condition? Increased capillary nonionic pressureDecreased interstitial nonionic pressure Increased capillary hydrostatic pressure Increased interstitial hydrostatic pressure 3 of 40 Which of the following can cause swollen feet to develop? Increased ATOP Chloride movement out of the cell An+ movement into the cell Decreased nonionic pressure 4 Of 40 What Is the role of cytokines In cell reproduction? Provide growth factor for tissue growth and development Bloc k progress of cell reproduction through the cell cycle Restrain cell growth and development Provide nutrients for cell growth and development Sodium and water accumulation in an injured cell are a direct result of which of the allowing?Decreased ATOP production Sororities Ribosome detachment Dehydration 6 of 40 A cell that does not contain a multiple of 23 chromosomes is called a diploid upload unplanned haploid 7 of 40 cell. Which of the following molecules is likely to accumulate in dead or dying tissues? Calcium Protein Uric acid Melanin 8 of 40 A condition in which a single chromosome is missing in each cell is called a haploid condition. An autos. A monsoons. Down Syndrome. 9 of 40 A child is born with blue eyes (b). The child's mother has blue eyes, and the father has brown eyes. Which of the following represents the father?Bibb Ebb 10 of 40 RNA directs the synthesis of protein through which process? Transcription Translation Translation 11 of 40 Which of the following problem s results in increased capillary hydrostatic pressure and the formation of edema? Renal failure Hemorrhaging Liver failure All of the above 12 of 40 The Eukaryotic cell consists of which of the following three components? The plasma membrane, the cytoplasm, and intracellular organelles The plasma membrane, the extracurricular membrane, and lagan's Cell Junctions, the extracurricular membranes, and proteins Water, proteins, and receptors 13 of 40The process by which cells program themselves to die is called corollary's. Optimism. Opinions. Necrosis. 31 of 40 Steven has Dutchmen muscular dystrophy. He inherited this condition from his mother only. Father only. Mother and father. Mother or father. The outward manifestation of a disease, which is often influenced by both genes and environment, is called the disease genotype. Allele. Phenotype. Dominance. 33 of 40 An increase in antipathetic hormone (DAD) secretion will result in which of the following changes? Increased serum sodium con centrations Decreased serum sodium concentrations Increased serum potassium concentrationsDecreased serum potassium concentrations 34 of 40 Which phase of catabolic produces the most ATOP? Digestion Glycoside Oxidation Citric acid cycle 35 of 40 Mutations can result in abnormal DNA. RNA. Proteins. DNA, RNA, and proteins. 36 of 40 Mutations that do not change the amino acid sequence and thus have no consequence are termed mutations. Frameset spontaneous silent misses 37 of 40 CT scan reveals that the patient is suffering from cerebral edema. This type of edema is referred to as localized edema. Generalized edema. Pitting edema. Lymphoma. 38 of 40 Which of the following is not an accepted theory of aging?Cellular aging results from wear and tear over the course of a lifetime. The degeneration of extracurricular materials such as collagen contributes to aging. The process of transcription during protein synthesis becomes more error-prone as a cell ages. The genetic mechanisms of aging are programmed into a cell's DNA. Question 39 of 40 Cellular atrophy involves an increase in cell size. A decrease in cell size. An increase in the number of cells. A decrease in the number of cells. 40 of 40 Which of the following electrolytes is found in the highest concentrations in the intracellular fluid (ICE)? Sodium Magnesium Potassium

Writing Prompts

Do you agree or disagree with the following statement? Parents are the best teachers. Use specific reasons and examples to support your answer. Children spend a lot of time watching television. Have you thought much about the programs and advertisements you watch. Can you tell the difference between what happens on television and what is real? Write a passage that demonstrates that you do know the difference. Customizing the Questions You can modify the questions by changing the audience. I've generally focused the writer's attention on writing a letter to the editor of a local community newspaper or the school paper. You can modify the assignment by asking students to write a letter to the principal, to a teacher, to the school board, to the governor, to a state senator (or similar politician), to the city board, to their classmates, to the PTA president (or other officers), and so on. College students might write to students attending the high school that they graduated from. 1. [School Uniforms] There has been a problem in local schools with discipline and violence. Your school board has decided to institute a school uniform policy in order to cut down on these problems, based on the positive examples that they have seen at other schools. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position on this issue and supporting it with convincing reasons. 2. [Locker Searches/Personal Searches] The principal at your school has instituted random locker and backpack/bookbag searches to check for guns, knives, and other weapons. Anyone caught with these weapons will be immediately suspended. The principal argues that the random searches will not only guard against illegal weapons at school but will also will help students feel safer. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 3. [Too Much Homework] Some of the parents at your school have started a campaign to limit the homework that teachers can assign to students. Teachers at your school have argued that the homework is necessary. What is your position? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 4. [Censorship] Your local public library has come under criticism for allowing patrons under the age of 18 to check out books that are unacceptable. The books are either explicit, describe graphic violence, or use questionable language. Most recently, a high school senior checked out James Joyce's Ulysses. The student's parents did not approve of the student reading the book and complained to the town council. As a result, the council is considering removing all questionable books from the library. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 5. [Litter] A litter problem has developed on your school's campus. Students are throwing trash on the ground, leaving empty soda cans and bottles outside on benches, and dropping napkins and other trash on the cafeteria floor rather than carrying them to the trash can. Your principal has asked students to take more care, but the litter problem persists. The principal has reacted by canceling all after-school activities until the problem is taken care of. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 6. [New Highway Exit] The state has created a plan to add a second highway exit to help shoppers access a busy shopping mall. The only problem is that the new exit will move the access road 500 yards closer to a near-by elementary school. Teachers and parents at the school complain that moving the road closer will increase noise at the school and provide unnecessary distractions. The state planners have included privacy fences to help cut down on the problems, but the protesters are unsatisfied. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 7. [Computers in the Classroom] As part of a new technology initiative, your local school district is increasing the number of computers in every school. The district plan provides for two computers in every classroom. Teachers at your school are lobbying instead to place all the computers together, creating two computer-based classrooms so that all students in a class can work at the computers together, rather than only one or two students at a time. The district is worried about the additional cost of creating and maintaining these special classrooms and is concerned about how access to the classrooms can be provided fairly and efficiently. What is your position on this issue? Write a letter to the editor of your local newspaper stating your point of view and supporting it with convincing reasons. 8. Bilingual Education] As part of a proposed educational initiative in your state, local school districts are responsible for providing required courses in both English language and Spanish language in order to increase the success of their programs. Because your state has a large population of Spanish speakers, the state education department believes that teaching these students in their first languag e will help them learn better and more quickly. Because of the limited budget, however, the local school board is concerned that they may not be able to provide the additional teachers or training needed for this program. They fear that they will lose state funding and accreditation even though 90% of the district's students pass their achievement tests on the first try. What is your position on this issue? Write a letter to the editor of your local newspaper stating your point of view and supporting it with convincing reasons. 9. [Grade Scale Change] One of the biology teachers at your school has decided to change from a ten-point grade scale (100 to 90 is an A, 89 to 80 is a B, etc. ) to a seven-point grade scale (100 to 93 is an A, 92 to 85 is a B, etc. ). The teacher is trying to encourage students to put more effort into their classes by raising the requirements. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position and supporting it with convincing reasons. 10. [Online Schools] The state department of education has provided funding for an experimental online school. All the classes will take place on the Internet, using email, online chat, and the world wide web. The students taking classes at this new online school will never meet each other face-to-face. They will only interact online with each other and with their teachers. The state is hoping this program will provide fairer educational access to students in outlying, rural areas. Opponents of the program argue that because of their lack of interaction with other students in a traditional classroom, the students who attend this online school will not develop the social skills that should be a component of their education. What is your position on this issue? Write a letter to the editor of your local newspaper stating your position on this issue and supporting it with convincing reasons.

Thursday, August 15, 2019

Fast food restauran Essay

For each category I analyse I will show the male and female results in comparison then summarise what I interpret from the results below. Due to the fact that there are more females in Stotfold than there are males. The females’ preferences will have a larger bearing on any possible fast food restaurant to be developed. As there are unequal results from both genders I have converted my results to percentages before showing them on the graph. Visit Frequency Below is a bar chart comparing the visit frequency of male and female. I have shown the data on a bar chart because it is easier to compare. Male and female do not differ significantly as far as visit frequency is concerned. Most customers visit a fast food restaurant every two weeks, which, if there are enough customers, is sufficient to keep a fast food business afloat. Most Important Feature The bar chart below shows what both male and female consider to be the most important feature of a fast food restaurant. This just confirms what the general analysis stated: – that if a business is to succeed its customers must have confidence in its hygiene. The bar chart below shows a comparison between male and female fast food type preferences. The females’ main preferences are already well catered for in Stotfold. Kebab shops are, however , hard to find in this area and are highly popular among males. If a Kebab restaurant opened in Stotfold it could target male customers, although I have noticed that it is not just younger males that enjoy kebabs as one might have expected. Cost The chart below shows what male and females expect to pay for a fast food meal for one. This chart shows that more men are prepared to pay more for their meal than women. I think this can be shown more clearly so here is another chart showing the same information but with different price categories. This shows that the majority of males expect to pay over i 4 whereas females expect to pay below. This shows the male market is more profitable providing production and retail costs are kept to a minimum, 4) Place Information about Stotfold Stotfold is a growing town. The development of new houses in the area means that by 2004 the population will have risen by nearly 25%. The population of Stotfold in 2000 was 6680. In 2004 it is estimated that it will rise to 8180. There are also plans to develop a leisure centre in Stotfold, which may attract even more people to the area. Stotfold is on the border between Bedfordshire and Hertfordshire; there are many fast food restaurants in Hertfordshire, including large franchises, which would pose a threat to small companies opening up in the area. In my research I have collected information from Bedfordshire but the well-established businesses in Hertfordshire should be taken into account when deciding to start a new company in the area. There is an area of land on the outskirts of Stotfold by the old doctors surgery. It has planning permission and there is a possibility of a Sports facility being put up there. It is on a main road so has good access and a cycle path leading past the area. It would be extremely expensive to develop this land but if a new Sports facility were to be opened there it may be possible to incorporate a new restaurant on the complex. Below is a map showing the location I referred to. The area is within the shaded rectangle.